بررسی دریافت درشت مغذی ها در مبتلایان به سندرم تخمدان پلی کیستیک به تفکیک زیرگروه بر اساس معیار روتردام

Background: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in reproductive-age women in Iran. Nutrition is considered as one of the probable affecting factors on the severity of PCOS. Till date, there is no study on dietary intakes of PCOS phenotypes, separately. Thus, this study sought to assess the dietary intake of macronutrients in four phenotypes of PCOS. Methods: This case-control study which was approved by the Medical Ethics Committee of Tarbiat Modares University was conducted by convenience sampling method on 182 patients eligible for the study. Subjects were classified according to the Rotterdam criteria: A (n=41), B (n=33), C (n=40), D (n=37) and control (without PCOS) (n=31). Assessment of dietary intake (Macronutrients), was carried out by valid-reliable 168-items food frequency questionnaire. Statistical analysis was performed using SPSS22 software and Kruskal-Wallis (KW) test followed by appropriate post hoc test, Mann-Whitney U (MW). Significant P-value was considered 0.05 for KW test and 0.005 for MW (based on Bonferroni correction). Results: Total fat intake in subgroups A, B and C was lower than controls (P<0.001). Phenotype A had a lower intake of PUFA and MUFA (P<0.005), and a higher intake of trans fatty acids (P<0.001) compared with controls. All PCOS phenotypes had a higher consumption of carbohydrates and a lower fiber consumption than controls (P<0.001). There was no significant difference between different phenotypes of PCOS with each other and with the control group in terms of saturated fat, protein and soluble fiber (P> 0.05). Conclusion: It is suggested that the complications associated with PCOS can be greatly reduced by changing in nutritional situation of these patients. It is a major step towards improving the status of these patients. &nbsp;